Intravital microscopy as a tool to study drug delivery in preclinical studies

Intravital microscopy

Intravital microscopy is an extremely powerful tool that enables imaging several biological processes in live animals. Recently, the ability to image subcellular structures in several organs combined with the development of sophisticated genetic tools has made possible extending this approach to investigate several aspects of cell biology. Here we provide a general overview of intravital micros...

A Localized, Quantitative Drug Delivery Tool for Neurotransmission Studies

Intravital microscopy

In principle, there is little difference between conventional microscopy methods and intravital microscopy; in practice, however, there are significant differences in the way images are acquired and processed and a number of unusual features are associated with the microscope mechanics and other accessories. This note describes the approaches that we have developed over the last few years at GC...

High-Resolution Intravital Microscopy

Cellular communication constitutes a fundamental mechanism of life, for instance by permitting transfer of information through synapses in the nervous system and by leading to activation of cells during the course of immune responses. Monitoring cell-cell interactions within living adult organisms is crucial in order to draw conclusions on their behavior with respect to the fate of cells, tissu...

a frame semantic approach to the study of translating cultural scripts in salingers franny and zooey

the frame semantic theory is a nascent approach in the area of translation studies which goes beyond the linguistic barriers and helps us to incorporate cognitive and cultural factors to the study of translation. based on rojos analytical model (2002b), which centered in the frames or knowledge structures activated in the text, the present research explores the various translation problems that...